Ethanone, 2-broMo-1-(3,5-dichlorophenyl)- (Related Reference) synthesis
- Product Name:Ethanone, 2-broMo-1-(3,5-dichlorophenyl)- (Related Reference)
- CAS Number:53631-13-3
- Molecular formula:C8H5BrCl2O
- Molecular Weight:267.93
14401-72-0
53631-13-3
i) Synthesis of 2-bromo-1-(3,5-dichlorophenyl)-1-ethanone: 1.03 mL (0.02 mol) of bromine was added dropwise to a 50 mL solution of acetic acid containing 3.77 g (0.019 mol) of 1-(3,5-dichlorophenyl)ethanone at room temperature. The reaction mixture was stirred continuously at room temperature for 12 hours. Upon completion of the reaction, the acetic acid was removed by distillation under reduced pressure to give a yellow solid precipitate, the target product 2-bromo-1-(3,5-dichlorophenyl)-1-ethanone in 81% yield.
14401-72-0
147 suppliers
$9.00/1g
53631-13-3
64 suppliers
$22.00/250mg
Yield:53631-13-3 81%
Reaction Conditions:
with bromine in acetic acid;
Steps:
18.i EXAMPLES 18
i) 2-Bromo-1-(3,5-dichlorophenyl)-1-ethanone: 1.03 ml (0.02 mol) of bromine are added, at room temperature, to 3.77 g (0.019 mol) of (3,5-dichlorophenyl)ethanone in solution in 50 ml of acetic acid. After stirring for 12 hours, evaporation of the acetic acid leads to the production of a yellow precipitate: 2-bromo-1-(3,5-dichlorophenyl)-1-ethanone (yield 81%).
References:
US5945382,1999,A
2905-62-6
358 suppliers
$13.43/1gm:
53631-13-3
64 suppliers
$22.00/250mg