(2E)-3-(4-chlorophenyl)-1-(3,4-dimethoxyphenyl)prop-2-en-1-one synthesis
- Product Name:(2E)-3-(4-chlorophenyl)-1-(3,4-dimethoxyphenyl)prop-2-en-1-one
- CAS Number:53744-30-2
- Molecular formula:C17H15ClO3
- Molecular Weight:302.75
Yield:53744-30-2 98%
Reaction Conditions:
with sodium hydroxide in methanol at 20;Claisen-Schmidt Condensation;
Steps:
3.2. General Procedure for Preparation of Substituted Chalcones (1-22)
General procedure: A mixture of sodium hydroxide (12 mmol), the aldehyde (3 mmol) and the ketone (3 mmol) in methanol (10 mL) was stirred at room temperature. After the reaction completion byTLC, the mixture was filtered at reduced pressure and the solid collected and washed with cold methanol.
References:
Sakata, Renata P.;Figueiró, Micheli;Kawano, Daniel F.;Almeida, Wanda P. [Medicinal Chemistry,2017,vol. 13,# 7,p. 654 - 663]
197227-41-1
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