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3-aminothieno[2,3-b]pyridine-2-carboxylic acid amide synthesis

4synthesis methods
-

Yield:55557-48-7 82%

Reaction Conditions:

with sodium methylate in N,N-dimethyl-formamide at 20; for 1 h;

References:

Morwick, Tina;Berry, Angela;Brickwood, Janice;Cardozo, Mario;Catron, Katrina;DeTuri, Molly;Emeigh, Jonathan;Homon, Carol;Hrapchak, Matt;Jacober, Stephen;Jakes, Scott;Kaplita, Paul;Kelly, Terence A.;Ksiazek, John;Liuzzi, Michel;Magolda, Ronald;Mao, Can;Marshall, Daniel;McNeil, Daniel;Prokopowicz II, Anthony;Sarko, Christopher;Scouten, Erika;Sledziona, Cynthia;Sun, Sanxing;Watrous, Jane;Wu, Jiang Ping;Cywin, Charles L. [Journal of Medicinal Chemistry,2006,vol. 49,# 10,p. 2898 - 2908]