3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXY-ALPHA,ALPHA-DIMETHYLBENZENEPROPANAL synthesis
- Product Name:3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXY-ALPHA,ALPHA-DIMETHYLBENZENEPROPANAL
- CAS Number:56189-68-5
- Molecular formula:C19H30O2
- Molecular Weight:290.44
128-39-2
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56189-68-5
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Yield:56189-68-5 238 g (92%)
Reaction Conditions:
in methanol;water;
Steps:
2 Example 2
Example 2 125 g (1 mol) of 80% strength aqueous 2,2-dimethyl-3-hydroxypropanal (crude mixture from the synthesis, reduced to a water content of 20% by distillation), 185 g (0.9 mol) of 2,6-di-t-butylphenol, 12 g (0.11 mol) of 40% strength aqueous dimethylamine and 700 g of methanol are reacted in a stirred autoclave at 180° C. and under the autogenous pressure of 20-30 bar for 10 h. Workup of the reaction mixture by distillation yields 238 g (92%) of 3-(3,5-di-t-butyl-4-hydroxyphenyl)-2,2-dimethylpropanal (boiling point 126°-127° C.; melting point 75°-77° C.).
References:
US5304685,1994,A
