ChemicalBook CAS DataBase List (R)-tert-butyl 2-(methoxymethyl)pyrrolidine-1-carboxylate

(R)-tert-butyl 2-(methoxymethyl)pyrrolidine-1-carboxylate synthesis

3synthesis methods

Product Name:(R)-tert-butyl 2-(methoxymethyl)pyrrolidine-1-carboxylate
CAS Number:578741-10-3
Molecular formula:C11H21NO3
Molecular Weight:215.2893

PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-METHYL ESTER

145681-01-2
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$25.00/1g

(R)-tert-butyl 2-(methoxymethyl)pyrrolidine-1-carboxylate

578741-10-3
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: 49 percent / Candida antarctica lipase / aq. phosphate buffer / 25 h / 30 °C / pH 6.8
2: 93 percent / NaBH₄; LiCl
3: 94 percent / NaH / tetrahydrofuran / -78 - 20 °C

References:

Kurokawa, Masayuki;Shindo, Takeyuki;Suzuki, Masumi;Nakajima, Nobuyoshi;Ishihara, Kohji;Sugai, Takeshi [Tetrahedron Asymmetry,2003,vol. 14,# 10,p. 1323 - 1333]

73323-65-6 Synthesis

73323-65-6
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$10.00/5g

578741-10-3
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References

15761-39-4
595 suppliers
$5.00/10g

578741-10-3
14 suppliers
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References