6-bromo-3-(trifluoromethyl)imidazo[1,5-a]pyridine synthesis
- Product Name:6-bromo-3-(trifluoromethyl)imidazo[1,5-a]pyridine
- CAS Number:1262619-64-6
- Molecular formula:C8H4BrF3N2
- Molecular Weight:265.03
173999-23-0
140 suppliers
$24.00/100mg
407-25-0
475 suppliers
$9.00/1g
1262619-64-6
15 suppliers
inquiry
Yield:1262619-64-6 72%
Reaction Conditions:
Stage #1: C-(5-bromo-pyridin-2-yl)-methylaminewith triethylamine in tetrahydrofuran at 20; for 0.0833333 h;Inert atmosphere;Schlenk technique;
Stage #2: trifluoroacetic anhydride in tetrahydrofuran at 0 - 20; for 0.5 h;Inert atmosphere;Schlenk technique;
References:
Sch?fer, Gabriel;Ahmetovic, Muhamed;Abele, Stefan [Organic Letters,2017,vol. 19,# 24,p. 6578 - 6581] Location in patent:supporting information