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6-hydroxymethylpurine riboside synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: zinc / tetrahydrofuran / 10 - 15 °C
1.2: 94 percent / Pd(PPh3)4 / tetrahydrofuran / 8 h / 20 °C
2.1: 81 percent / MeONa / methanol / 20 °C

References:

Silhar, Peter;Pohl, Radek;Votruba, Ivan;Hocek, Michal [Collection of Czechoslovak Chemical Communications,2005,vol. 70,# 10,p. 1669 - 1695]