7-CHLORO-1-(2-CHLOROPHENYL)-1-OXOHEPTANE synthesis
- Product Name:7-CHLORO-1-(2-CHLOROPHENYL)-1-OXOHEPTANE
- CAS Number:898768-20-2
- Molecular formula:C13H16Cl2O
- Molecular Weight:259.17
6294-17-3
208 suppliers
$10.00/1g
609-65-4
336 suppliers
$21.00/25g
898768-20-2
9 suppliers
$366.00/1g
Yield:898768-20-2 63%
Reaction Conditions:
Stage #1: 1-bromo-6-chlorohexanewith magnesium;lithium chloride;zinc(II) chloride in tetrahydrofuran at 20; for 0.666667 h;Inert atmosphere;
Stage #2: with copper(I) cyanide di(lithium chloride) in tetrahydrofuran at -30;Inert atmosphere;
Stage #3: o-chlorobenzoyl chloride in tetrahydrofuran at -30;Inert atmosphere;
References:
Bluemke, Tobias D.;Piller, Fabian M.;Knochel, Paul [Chemical Communications,2010,vol. 46,# 23,p. 4082 - 4084] Location in patent:supporting information; experimental part