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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide

diethyl [[(3-chloro-4-fluorophenyl)amino]methylene]malonate synthesis

3synthesis methods
367-21-5 Synthesis
3-Chloro-4-fluoroaniline

367-21-5
504 suppliers
$5.00/25g

Diethyl ethoxymethylenemalonate

87-13-8
426 suppliers
$5.00/5g

diethyl [[(3-chloro-4-fluorophenyl)amino]methylene]malonate

70032-30-3
19 suppliers
inquiry

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Yield:70032-30-3 100%

Reaction Conditions:

at 120 - 130; for 2 h;

References:

Koga, Hiroshi;Itoh, Akira;Murayama, Satoshi;Suzue, Seigo;Irikura, Tsutomu [Journal of Medicinal Chemistry,1980,vol. 23,# 12,p. 1358 - 1363]

Propanedioic acid,2-(2,2,2-trichloroethylidene)-, 1,3-diethyl ester

27971-92-2
0 suppliers
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diethyl [[(3-chloro-4-fluorophenyl)amino]methylene]malonate

70032-30-3
19 suppliers
inquiry

References
Diethyl malonate

105-53-3
732 suppliers
$5.00/25g

diethyl [[(3-chloro-4-fluorophenyl)amino]methylene]malonate

70032-30-3
19 suppliers
inquiry

References