Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, methyl ester, (1R,2R,4R)- (9CI) synthesis
2synthesis methods
- Product Name:Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, methyl ester, (1R,2R,4R)- (9CI)
- CAS Number:72203-34-0
- Molecular formula:C9H12O2
- Molecular Weight:152.1904
Yield:5722-94-1 95%
Reaction Conditions:
with chiral borane catalyst (1R,2R)-1a (Ar = 1-Naph) in dichloromethane at -78; for 12 h;Product distribution;Mechanism;other dienophile; the effect of catalyst polarizability on the enantioselectivity;
References:
Hawkins, Joel M.;Loren, Stefan;Nambu, Mitch [Journal of the American Chemical Society,1994,vol. 116,# 5,p. 1657 - 1660]
![2-Oxazolidinone, 3-[(1R,2R,4R)-bicyclo[2.2.1]hept-5-en-2-ylcarbonyl]-4-(1-methylethyl)-, (4S)-](/CAS/20210305/GIF/90719-33-8.gif)