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8-BROMO-2-CHLORO-3-(TRIFLUOROMETHYL)QUINOLINE synthesis

5synthesis methods
81290-20-2 Synthesis
(Trifluoromethyl)trimethylsilane

81290-20-2
393 suppliers
$13.00/1g

590371-88-3 Synthesis
Quinoline, 8-bromo-2-chloro-3-iodo-

590371-88-3
18 suppliers
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8-BROMO-2-CHLORO-3-(TRIFLUOROMETHYL)QUINOLINE

590372-03-5
14 suppliers
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Yield:590372-03-5 64%

Reaction Conditions:

with potassium fluoride;copper(l) iodide in 1-methyl-pyrrolidin-2-one at 50; for 20 h;

References:

Cottet, Fabrice;Marull, Marc;Lefebvre, Olivier;Schlosser, Manfred [European Journal of Organic Chemistry,2003,# 8,p. 1559 - 1568]