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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List 1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE
85532-75-8

1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE synthesis

2synthesis methods
Ethyl chloroformate

541-41-3
0 suppliers
$19.39/5g

Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

1000210-73-0
0 suppliers
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1-(2-Chlorophenyl)-3-isoquinolinecarboxylic acid

89242-09-1
14 suppliers
$226.38/250mg

1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE

85532-75-8
122 suppliers
$40.00/5mg

-

Yield:-

Reaction Conditions:

with hydrogenchloride;triethylamine in toluene

Steps:

44 N-methyl N-1-(S)-methyl propyl) 1-(2-chloro phenyl) isoquinoline 3-carboxamide
EXAMPLE 44 N-methyl N-1-(S)-methyl propyl) 1-(2-chloro phenyl) isoquinoline 3-carboxamide Operations are carried out as for Example 7, starting from 1.7 g of 1-(2-chloro phenyl) isoquinoline 3-carboxylic acid, 2.1 g of triethylamine, 0.75 g of ethyl chloroformate and 0.96 g of N-methyl 2(S)-butanamine, HCl in 60 ml of toluene. After chromatography and recrystallization in cyclohexane, 0.5 g of N-methyl N-(1-(S)-methyl propyl) 1-(2-chlorophenyl) isoquinoline 3-carboxamide melting at 134° C. is obtained. αD27 =+53.7° (0.5% in CHCl3).

References:

Pharmuka Laboratoires US4499094, 1985, A

3-?Isoquinolinecarboxam?ide, 1-?(2-?chlorophenyl)?-?N-?(1-?methylpropyl)?-

124236-61-9
7 suppliers
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Iodomethane

74-88-4
357 suppliers
$15.00/10g

1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE

85532-75-8
122 suppliers
$40.00/5mg

References

1-(2-CHLOROPHENYL)-N-METHYL-N-(1-METHYLPROPYL)-3-ISOQUINOLINECARBOXAMIDE Related Search:

1-Tetradecanol 6-Methyl-2-pyridinemethanamine 2-Picolylamine 3-Methylisoquinoline METHYLPYRIDIN-2-YLMETHYLAMINE DIHYDROCHLORIDE 3-isoquinolinecarboxaldehyde N-(pyridin-2-ylmethyl)propan-1-amine CHEMBRDG-BB 9070750 2-Pyridinecarboxamide,6-methyl-(9CI)