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2,2,2-TRIFLUORO-1-(6-METHOXY-NAPHTHALEN-2-YL)-ETHANONE synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / -40 °C
2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C
2.2: 0.5 h / -78 °C

References:

Trost, Barry M.;Debien, Laurent [Journal of the American Chemical Society,2015,vol. 137,# 36,p. 11606 - 11609]

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