5-CHLORO-2-METHOXY-4-METHYLBENZENESULFONYL CHLORIDE synthesis
- Product Name:5-CHLORO-2-METHOXY-4-METHYLBENZENESULFONYL CHLORIDE
- CAS Number:889939-48-4
- Molecular formula:C8H8Cl2O3S
- Molecular Weight:255.12
13334-71-9
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889939-48-4
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Yield:889939-48-4 75.6%
Reaction Conditions:
with sulfuryl dichloride at 20; for 1 h;Cooling with ice;
Steps:
7.B Preparation of 5-chloro-2-methoxy-4-toluenesulfonyl chloride
In a 250 mL three-necked flask was added 1-chloro-4-methoxy-2-methylbenzene (18.7 g, 119.4 mmol)Under ice-cooling, sulfuryl chloride (27.8 g, 238.9 mmol) was slowly added dropwise and reacted at room temperature for 1 h. After completion of the reaction, the reaction solution was poured into ice water and analyzed.A large amount of solid, suction filter, filter cake vacuum drying, in 5-chloro-2-methoxy-4-toluenesulfonyl chloride 23.1g, the yield of 75.6%.
References:
CN106674065,2017,A Location in patent:Paragraph 0055; 0058-0059
59-50-7
444 suppliers
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889939-48-4
45 suppliers
$25.00/1g