1,2,3-Trimethyl-1-(2-propen-1-yl)-1H-benz[e]indolium bromide synthesis

Yield:891503-79-0 70.9%

Reaction Conditions:

in ethanol at 62; for 10 h;

Steps:

1

Example 1; Preparation of Hexafluorophosphate of Compound No. 4; In a reaction flask were put 0.050 mol of 1,2,3-trimethylbenzindole, 0.090 mol of 3-bromopentene, and 16.5 g of ethanol and allowed to react at 62° C. for 10 hours. The reaction mixture was cooled to room temperature, and 40 ml of ethyl acetate was slowly added thereto. The crystals thus precipitated were collected by filtration and dried in vacuo at 80° C. for 2 hours to give an intermediate, 1,2,3-trimethyl-3-propenylbenzindolenium bromide, as white crystals in a yield of 70.9%.

References:

US2008/33179,2008,A1 Location in patent:Page/Page column 12