ChemicalBook CAS DataBase List 9,9-Bis(4-hydroxyphenyl)fluorene

9,9-Bis(4-hydroxyphenyl)fluorene synthesis

6synthesis methods

Product Name:9,9-Bis(4-hydroxyphenyl)fluorene
CAS Number:3236-71-3
Molecular formula:C25H18O2
Molecular Weight:350.41

486-25-9

108-95-2

3236-71-3

Example 4 Synthesis of 9,9-bis-(4-hydroxyphenyl)-fluorene: 20 moles of phenol containing 9 wt. % water were stirred in an autoclave, followed by the addition of 1 mole of zinc chloride and 10 moles of fluorenone, which was allowed to dissolve. 5 moles of gaseous hydrogen chloride was passed into the stirred mixture and the reaction mixture was reacted at 70°C for 4 hours. Upon completion of the reaction, the mixture was dissolved in 5 liters of isopropanol at 60 °C. The resulting solution was poured into 10 times the volume of water under vigorous stirring to precipitate 3.4 kg of 9,9-bis-(4-hydroxyphenyl)-fluorene in 97% yield as a yellow solid.

486-25-9 Synthesis

486-25-9
483 suppliers
$5.00/25g

108-95-2 Synthesis

108-95-2
767 suppliers
$14.00/25g

3236-71-3
417 suppliers
$6.00/5g

Yield:3236-71-3 97%

Reaction Conditions:

with hydrogenchloride in Zinc chloride;lithium hydroxide monohydrate;isopropanol;

Steps:

4 9,9-bis-(4-hydroxyphenyl)-fluorene

EXAMPLE 4 9,9-bis-(4-hydroxyphenyl)-fluorene 20 moles of phenol containing 9% by weight of water were stirred in an autoclave and then one mole of zinc chloride and 10 moles of fluorenone were dissolved therein. Then, 5 moles of gaseous hydrogen chloride were added to the stirred mixture and the mixture was reacted at 70° C. for 4 hours. The reaction mixture was then dissolved in 5 liters of isopropanol at 60° C. and the solution was poured with vigorous stirring into a ten-fold volume of water to precipitate 3.4 kg of 9,9,-bis-(4-hydroxyphenyl)-fluorene (97% yield in the form of a yellow product.

References:

US4467122,1984,A

486-25-9 Synthesis

486-25-9
483 suppliers
$5.00/25g

108-95-2 Synthesis

108-95-2
767 suppliers
$14.00/25g

620-92-8 Synthesis