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ChemicalBook CAS DataBase List (S,S)-4,6-Bis(4-isopropyl-2-oxazolin-2-yl)-M-xylene
929896-22-0

(S,S)-4,6-Bis(4-isopropyl-2-oxazolin-2-yl)-M-xylene synthesis

2synthesis methods
-

Yield:929896-22-0 78%

Reaction Conditions:

Stage #1: (S)-valinol;4,6-dimethylisophthaloyl dichloridewith triethylamine in tetrahydrofuran at 20; for 2 h;
Stage #2: with methanesulfonyl chloride in tetrahydrofuran at 20; for 14 h;

References:

Ito, Jun-Ichi;Shiomi, Takushi;Nishiyama, Hisao [Advanced Synthesis and Catalysis,2006,vol. 348,# 10-11,p. 1235 - 1240]