ChemicalBook >> CAS DataBase List >>(S)-(+)-2-Amino-3-methyl-1-butanol
(S)-(+)-2-Amino-3-methyl-1-butanol
- CAS No.
- 2026-48-4
- Chemical Name:
- (S)-(+)-2-Amino-3-methyl-1-butanol
- Synonyms
- H-VAL-OL;L-Valino;L-Val-ol;-(+)-VaL;H-VALINOL;L-VALINOL;L-VALINAL;L-Valanol;S-VALINOL;H-L-VAL-OL
- CBNumber:
- CB9319657
- Molecular Formula:
- C5H13NO
- Formula Weight:
- 103.16
- MOL File:
- 2026-48-4.mol
- MSDS File:
- SDS
- Melting point
- 30-34 °C
- alpha
- 16 º (c=10,EtOH)
- Boiling point
- 81 °C8 mm Hg(lit.)
- Density
- 0.926 g/mL at 25 °C(lit.)
- refractive index
- n
20/D 1.4548(lit.)
- Flash point
- 196 °F
- storage temp.
- Store at +2°C to +8°C.
- form
- Liquid After Melting
- pka
- 12.82±0.10(Predicted)
- color
- Clear slightly yellow
- optical activity
- [α]25/D +10°, c = 10 in H2O
- Water Solubility
- Soluble in water.
- Sensitive
- Air Sensitive
- BRN
- 1719137
- InChIKey
- NWYYWIJOWOLJNR-RXMQYKEDSA-N
- CAS DataBase Reference
- 2026-48-4(CAS DataBase Reference)
- NIST Chemistry Reference
- (S)-(+)-2-Amino-3-methyl-1-butanol(2026-48-4)
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280a-P305+P351+P338-P321-P332+P313-P337+P313 |
| Hazard Codes | Xi |
| Risk Statements | 36-36/37/38 |
| Safety Statements | 26-24/25-36 |
| WGK Germany | 3 |
| F | 10-23 |
| HazardClass | IRRITANT |
| HS Code | 29221980 |
(S)-(+)-2-Amino-3-methyl-1-butanol price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 186708 | (S)-(+)-2-Amino-3-methyl-1-butanol 96% | 2026-48-4 | 1g | $47.5 | 2022-05-15 | Buy |
| Sigma-Aldrich | 8.14082 | (S)-(+)-2-Amino-3-methyl-1-butanol for synthesis | 2026-48-4 | 1 mL | $57.6 | 2022-05-15 | Buy |
| Sigma-Aldrich | 186708 | (S)-(+)-2-Amino-3-methyl-1-butanol 96% | 2026-48-4 | 5g | $136 | 2022-05-15 | Buy |
| TCI Chemical | V0058 | L-Valinol >97.0%(GC)(T) | 2026-48-4 | 5g | $99 | 2022-04-27 | Buy |
| TCI Chemical | V0058 | L-Valinol >97.0%(GC)(T) | 2026-48-4 | 25g | $297 | 2022-04-27 | Buy |
(S)-(+)-2-Amino-3-methyl-1-butanol Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
L-Valinol is used as a reagent in the synthesis of simple 1,3-thiazolidine-2-thione derivatives which can exhibit fungicidal activity. L-Valinol is also used as a reagent in the synthesis of small-molecule inhibitors of MDM2-p53 protein-protein interaction (MDM2 inhibitors) in clinical trials for the treatment of cancer.
Uses
(S)-(+)-2-Amino-3-methyl-1-butanol can be used to prepare:
- Imines and oxazolines by reacting with aldehydes and nitriles, respectively.
- Chiral oxazoline derived multidentate ligands containing cyclophosphazene moiety.
Purification Methods
Purify S-valinol by vacuum distillation using a short Vigreux column (p 11). Alternatively it is purified by steam distillation. The steam distillate is acidified with HCl; the aqueous layer is collected and evaporated. The residue is dissolved in butan-1-ol, filtered and dry Et2O added to crystallise the hydrochloride salt (hygroscopic), m 113o. The free base can be obtained by suspending the salt in Et2O and adding small volumes of saturated aqueous K2CO3 until effervescence is complete and the mixture is distinctly alkaline. At this stage the aqueous layer should appear as a white sludge. The mixture is heated to boiling and refluxed for 30minutes (more Et2O is added if necessary). Purification of Biochemicals — Amino Acids and Peptides The Et2O layer is decanted off from the white sludge, the sludge is extracted twice with Et2O (by boiling for a few minutes), the combined organic layers are dried (KOH pellets), evaporated and the residue is distilled in a vacuum. [Nagao et al. J Org Chem 55 1148 1990, Beilstein 4 III 805.]
(S)-(+)-2-Amino-3-methyl-1-butanol Preparation Products And Raw materials
Global( 438)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chongqing Chemdad Co.,Ltd | +86-19923101450 | sales@chemdad.com | CHINA | 4000 | 58 |
| Henan DaKen Chemical CO.,LTD. | 371-66670886 | info@dakenchem.com | China | 15400 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | 0371-55170693 | info@tianfuchem.com | China | 22022 | 55 |
| Hangzhou FandaChem Co.,Ltd. | +8615858145714 | fandachem@gmail.com | China | 9513 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3013 | 60 |
| ATK CHEMICAL COMPANY LIMITED | 21-51619050 | ivan@atkchemical.com | China | 26810 | 60 |
| Zjartschem | +86-571-8723 8903 jocelynpan@zjarts.com | jocelynpan@zjarts.com | CHINA | 997 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29960 | 58 |
| Jinan Shengqi pharmaceutical Co,Ltd | 86+18663751872 | christine@shengqipharm.com | CHINA | 494 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 86-18871470254 | linda@hubeijusheng.com | CHINA | 28229 | 58 |
View Lastest Price from (S)-(+)-2-Amino-3-methyl-1-butanol manufacturers
| Image | Release date | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-02-25 | (S)-(+)-2-Amino-3-methyl-1-butanol
2026-48-4
|
US $0.00 / KG | 100g | 98%+ | 100kg | WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD | |
 |
2019-07-06 | (S)-(+)-2-Amino-3-methyl-1-butanol
2026-48-4
|
US $20.00 / KG | 25KG | 98% | 100kg | Career Henan Chemical Co |
-
- (S)-(+)-2-Amino-3-methyl-1-butanol
2026-48-4
- US $0.00 / KG
- 98%+
- WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
-
- (S)-(+)-2-Amino-3-methyl-1-butanol
2026-48-4
- US $20.00 / KG
- 98%
- Career Henan Chemical Co
2026-48-4((S)-(+)-2-Amino-3-methyl-1-butanol)Related Search:
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1-Amino-2-methyl-2-butanol
(R)-4-AMINO-2-METHYL-1-BUTANOL
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S/R-Valinol
(2S)-2-AMINO-3-METHYL-1BUTANOL
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L-VALINAL
(+)-L-VALINOL
L-(+)-VALINOL
L-VALINOL
L-2-AMINO-3-METHYL-1-BUTANOL
l-2-amino-3-methylbutan-1-ol
H-VALINOL
H-VAL-OL
H-L-VAL-OL
(2S)-2-AMINO-3-METHYL-BUTAN-1-OL
L-Valinol ,98%
(S)-2-Isopropyl-2-aminoethanol
(S)-(+)-2-Amino-3-methyl-1-butanol,96%
L-Valinol ,98% [ee: 95%]
L-Valinol ,95%
(S)-(+)-2-Amino-3-me
L-Valino
(S)-(+)-2-AMino-3-Methyl-1-butanol, 96% 1ML
(S)-(+)-2-AMINO-3-METHYL-1-BUTANOL FOR S
(S)-(+)-2-Amino-3-methyl-1-butanol(L-Valinal)
L-Valinol, 98%, ee: 95%
PKC PharMaceuticals, Inc.
L - valerian aMMonia alcohol
L-(+)-Valinol (S)-(+)-2-Amino-3-methyl-1-butanol L-2-Amino-3-methylbutan-1-ol
(S)-(+)-2-Amino-3-methyl-1-butanol 96%
L-Valinol Free Base
L-Valinol, ee: 95%
L-Valinol≥ 98% (GC)
L-Valinol,99%e.e.
L-Valinol,Elvitegravir intermediate
1-Butanol, 2-amino-3-methyl-, (S)-
(S)-(+)-2-Amino-3-methyl-1-butanol~H-Val-ol
Valinol,97%
(R)-(+)-2-Amino-3-methyl-1-butanolL-Valanol
L-Valinol(S)-(+)-2-Amino-3-methyl-1-butanol
L-Valanol
(S)-(+)-2-AMINO-3-METHYL-1-BUTANOL, 96% (95% EE/GLC)
L-Val-ol
(S)-2-AMINO-3-METHYL-1-BUTANOL 98.0%
1-Butanol, 2-amino-3-methyl-, (2S)-
S-VALINOL
(S)-2-AMINO-3-METHYL-L-BUTANOL
(S)-(+)-2-AMINO-3-METHYL-BUTANOL
(S)-2-AMINO-3-METHYL-BUTAN-1-OL
(S)-(+)-2-AMINO-3-METHYL-1-BUTANOL
(S)-2-AMINO-3-METHYL-1-BUTANOL
S-(-)-2-AMINO-3-METHYL-1-BUTANOL
H-Val-ol
(S)-(+)-2-Amino-3-methyl-1-butanol)
(S)-(+)-2-Amino-3-methyl-1-butanol fandachem
-(+)-VaL
(S)-(+)-2-Amino-3-methyl-1-butanol USP/EP/BP
2026-48-4
2046-48-4
226-48-4
AMINE
Peptide Synthesis
Specialty Synthesis
Organic Building Blocks