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AC-LEU-NHME synthesis

6synthesis methods
-

Yield:32483-15-1 15%

Reaction Conditions:

Stage #1: N-Ac-Leuwith 4-methyl-morpholine;pivaloyl chloride in tetrahydrofuran;N,N-dimethyl-formamide at -10; for 0.166667 h;
Stage #2: methylamine in tetrahydrofuran;N,N-dimethyl-formamide; for 1.5 h;

References:

Nathanael, Joses G.;Wille, Uta [Journal of Organic Chemistry,2019,vol. 84,# 6,p. 3405 - 3418]

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