Acethion synthesis
1synthesis methods
- Product Name:Acethion
- CAS Number:919-54-0
- Molecular formula:C8H17O4PS2
- Molecular Weight:272.32
Acethion is commercially produced through the esterification of mercaptoacetic acid with O,O-diethyl phosphorodithioate under controlled conditions to form ethyl 2-(diethoxyphosphinothioylthio)acetate. The synthesis involves reacting mercaptoacetic acid ethyl ester with diethyl phosphorodithioic chloride in an organic solvent such as toluene or dichloromethane, using a base like triethylamine to neutralize the hydrochloric acid byproduct. The reaction is conducted at low to moderate temperatures to preserve the integrity of the organophosphorus structure.
Yield:-
Reaction Conditions:
with triethylamine;benzene
References:
C.H.Boehringer Sohn FR1133785, 1955, A