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Adamantan-2-ylideneacetic acid synthesis

5synthesis methods
-

Yield:25220-07-9 72%

Reaction Conditions:

Stage #1: ethyl acetatewith lithium diisopropyl amide
Stage #2: 2-Adamantanone
Stage #3: with sulfuric acid

References:

Schreiner, Erwin P.;Wolff, Barbara;Winiski, Anthony P.;Billich, Andreas [Bioorganic and Medicinal Chemistry Letters,2003,vol. 13,# 24,p. 4313 - 4316]

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