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ChemicalBook CAS DataBase List BENZO[C][1,2,5]OXADIAZOLE-5-BORONIC ACID
426268-09-9

BENZO[C][1,2,5]OXADIAZOLE-5-BORONIC ACID synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: KOH / ethanol / 1 h / 60 °C
1.2: aq. NaOCl / 1 h / 0 °C
2.1: PPh3 / xylene / 3 h / 140 °C
3.1: 45 percent / n-BuLi; TMEDA; B(OEt)3 / tetrahydrofuran; pentane / 0.08 h / -100 °C

References:

Hersperger, Rene;Dawson, Janet;Mueller, Thomas [Bioorganic and Medicinal Chemistry Letters,2002,vol. 12,# 2,p. 233 - 235]