Benzoic acid, 2-hydroxy-, 1,1-dimethylethyl ester synthesis
- Product Name:Benzoic acid, 2-hydroxy-, 1,1-dimethylethyl ester
- CAS Number:23408-05-1
- Molecular formula:C11H14O3
- Molecular Weight:194.23
774-65-2
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$46.00/25mL
23408-05-1
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Yield:23408-05-1 87%
Reaction Conditions:
Stage #1: benzoic acid tert-butyl esterwith (TMP)2Cu(CN)Li2 in tetrahydrofuran at -78 - 0; for 2 h;Inert atmosphere;Schlenk technique;
Stage #2: with Cumene hydroperoxide in tetrahydrofuran;decane at -78; for 0.5 h;Inert atmosphere;Schlenk technique;regioselective reaction;Reagent/catalyst;
References:
Tezuka, Noriyuki;Shimojo, Kohei;Hirano, Keiichi;Komagawa, Shinsuke;Yoshida, Kengo;Wang, Chao;Miyamoto, Kazunori;Saito, Tatsuo;Takita, Ryo;Uchiyama, Masanobu [Journal of the American Chemical Society,2016,vol. 138,# 29,p. 9166 - 9171] Location in patent:supporting information
69-72-7
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36805-97-7
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$29.00/1g
23408-05-1
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85144-30-5
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