1,1'-Carbonyldiimidazole
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1,1'-Carbonyldiimidazole Properties
- Melting point:
- 117-122 °C(lit.)
- Boiling point:
- 288.83°C (rough estimate)
- Density
- 1.303 g/mL at 25 °C
- refractive index
- n20/D1.434
- storage temp.
- 2-8°C
- solubility
- Soluble in dimethylformamide.
- form
- Crystalline Powder
- pka
- 2.90±0.10(Predicted)
- color
- White to light cream
- PH
- 7.7 (50g/l, H2O, 20℃)
- PH Range
- 7.7 at 50 g/l
- Water Solubility
- Insoluble in water
- Sensitive
- Moisture Sensitive
- Merck
- 14,1819
- BRN
- 6826
- Stability:
- Stable, but moisture-sensitive. Incompatible with acids, strong oxidizing agents, water.
- InChIKey
- PFKFTWBEEFSNDU-UHFFFAOYSA-N
- CAS DataBase Reference
- 530-62-1(CAS DataBase Reference)
- FDA UNII
- 63A10X1FSP
- EPA Substance Registry System
- 1H-Imidazole, 1,1'-carbonylbis- (530-62-1)
SAFETY
- Risk and Safety Statements
| Symbol(GHS) |    GHS08,GHS05,GHS07 |
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|---|---|---|---|
| Signal word | Danger | ||
| Hazard statements | H302-H314-H351-H318 | ||
| Precautionary statements | P260-P264-P270-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P405-P501-P260h-P301+P330+P331-P303+P361+P353-P501a-P280-P305+P351+P338-P310 | ||
| Hazard Codes | C,Xi,Xn | ||
| Risk Statements | 22-34-36/37/38-40-36/38 | ||
| Safety Statements | 26-36/37/39-45-37/39-27-36/37 | ||
| RIDADR | UN 3263 8/PG 2 |
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| WGK Germany | 2 |
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| F | 10-21 | ||
| Hazard Note | Harmful/Corrosive/Moisture Sensitive | ||
| TSCA | T | ||
| HazardClass | 8 | ||
| PackingGroup | III | ||
| HS Code | 29332990 | ||
| Toxicity | LD50 orally in Rabbit: 1071 mg/kg |
1,1'-Carbonyldiimidazole price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 115533 | CDI reagent grade | 530-62-1 | 5g | $27.3 | 2020-08-18 | Buy |
| Sigma-Aldrich | 115533 | CDI reagent grade | 530-62-1 | 1kg | $825 | 2020-08-18 | Buy |
| TCI Chemical | C0119 | 1,1'-Carbonyldiimidazole [Coupling Agent for Peptides Synthesis] >97.0%(W) | 530-62-1 | 5g | $21 | 2020-06-24 | Buy |
| TCI Chemical | C0119 | 1,1'-Carbonyldiimidazole [Coupling Agent for Peptides Synthesis] >97.0%(W) | 530-62-1 | 25g | $65 | 2020-06-24 | Buy |
| Alfa Aesar | A14688 | 1,1'-Carbonyldiimidazole, 97% | 530-62-1 | 10g | $41.4 | 2020-06-24 | Buy |
1,1'-Carbonyldiimidazole Chemical Properties,Uses,Production
Chemical Properties
White crystalline powderUses
Used in the synthesis of peptides. Contains up to 10% imidazole.Uses
peptide coupling reagentUses
CDI is mainly employed to convert alcohols and amines into carbamates, esters, and ureas. It is also used in the synthesis of peptides and nucleoside triphosphates.Uses
1,1'-Carbonyldiimidazole is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Purification Methods
Crystallise it from *benzene or tetrahydrofuran in a dry-box and store it dry. [Hearn Methods Enzymol 135 102 1987, Beilstein 23/4 V 245.]1,1'-Carbonyldiimidazole Preparation Products And Raw materials
Raw materials
Preparation Products
2-(Boc-aminomethyl)-piperidine
3-oxo-3-phenyl-propanamide
5-(Pyridin-3-yl)-1H-pyrazole-3-carboxamide ,97%
3-Cyanomethylthiophene
4-AMINOMETHYL-BENZAMIDE
2,8-DICHLOROPYRIMIDO[5,4-D]PYRIMIDINE
Progabide
2-AMINO-5-BROMOBENZAMIDE
2-Ethylpiperazine
6-FLUORO-1H-PYRAZOLO[3,4-B]PYRIDINE-3-CARBONITRILE
Pazufloxacin
5-BROMOTHIOPHENE-2-CARBONITRILE
N-Heptafluorobutyrylimidazole
4-(Boc-Aminomethyl)piperidine
8-METHOXY-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID AMIDE
2-chloro-5-cyanopyridine
7-HYDROXY-2-OXO-2H-CHROMENE-3-CARBOXYLIC ACID AMIDE
1-Boc-2-Methylpiperazine
3-(1H-INDOL-3-YL)-1-PROPANAMINE
1-(4-ACETYLPIPERIDINO)ETHAN-1-ONE
5-BROMO-2-BENZOXAZOLINONE 97
isoglutamine
3-BROMOTHIOPHENE-2-CARBOXAMIDE
1-Boc-4-(aminomethyl)piperidine
2,3-DIAMINONAPHTHALENE
4-N-BOC-Aminopiperidine
5-AMINO-3-PYRIDINECARBONITRILE
4-Cyanopiperidine
1,3-THIAZOLIDIN-2-ONE
1,1'-Carbonyldiimidazole Suppliers
Global( 625)Suppliers
| Supplier | Tel | Fax | Country | ProdList | Advantage | |
|---|---|---|---|---|---|---|
| Shaanxi Yikanglong Biotechnology Co., Ltd. | 17791478691 |
yklbiotech@163.com | CHINA | 297 | 58 | |
| Nantong Xiaochang Pharmaceutical Trading Co., Ltd. | 17602153959 0513-81283365- |
sales8@btcpharm.com | CHINA | 286 | 58 | |
| HENAN BON INDUSTRIAL CO.,LTD | 0371-55170695 |
info@hnbon.com | CHINA | 26744 | 58 | |
| Hebei Xibaijie Biotechnology Co., Ltd. | 0086 15232103582 |
aiana@hbxibaijie.com | CHINA | 636 | 58 | |
| Capot Chemical Co.,Ltd. | +86（0）13336195806 +86-571-85586718 |
+86-571-85864795 | sales@capotchem.com | China | 19932 | 60 |
| Henan DaKen Chemical CO.,LTD. | +86-371-55531817 |
info@dakenchem.com | CHINA | 21734 | 58 | |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
010-60279497 | sales01@cooperate-pharm.com | CHINA | 1817 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | 0371-55170693 |
0371-55170693 | info@tianfuchem.com | CHINA | 22622 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +8618017249410 +86-021-57951555 |
+86-021-57951555 | jack.li@time-chemicals.com | CHINA | 1365 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +86 21 5161 9050/ 5187 7795 |
+86 21 5161 9052/ 5187 7796 | ivan@atkchemical.com | CHINA | 25016 | 60 |
Related articles
- What is 1,1'-Carbonyldiimidazole?
- 1,1'-Carbonyldiimidazole (CDI) is an organic compound with the molecular formula (C3H3N2) 2CO. It is a white crystalline solid....
- Jan 2，2020
View Lastest Price from 1,1'-Carbonyldiimidazole manufacturers
| Image | Release date | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-12-25 |
N,N-Carbonyldiimidazole 530-62-1 |
US $80.00-90.00 / KG | 1KG | >99% | 20tons | Anhui Rencheng Technology Co., Ltd | |
 |
2020-12-03 |
N, N-Carbonyldiimidazole 530-62-1 |
US $100.00 / KG | 1KG | 99 | 5tons | Hebei Chisure Biotechnology Co.LTD | |
 |
2020-12-09 |
N, N-Carbonyldiimidazole 530-62-1 |
US $100.00 / KG | 10IU | 99% | 10 | Hebei Henghe Import and Export Trading Co. LTD |
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