CIS-(1S,2R)-1N-CBZ-CYCLOHEXANE-1,2-DIAMINE synthesis
- Product Name:CIS-(1S,2R)-1N-CBZ-CYCLOHEXANE-1,2-DIAMINE
- CAS Number:1067631-21-3
- Molecular formula:C14H20N2O2
- Molecular Weight:248.32
2205-32-5
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1067631-21-3
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Yield:-
Steps:
Multi-step reaction with 8 steps
1.1: isobutyric acid / toluene / 2 h / Heating
2.1: sodium borohydride; isobutyric acid / toluene / 2 h / 0 °C
2.2: 458 mg / H2 / Pd(OH)2/C / methanol / 24 h / 50 °C / 38002.6 Torr
3.1: 75 percent / 2 h / 150 °C
4.1: thionyl chloride; dimethylformamide / CH2Cl2 / 1 h / 20 °C
5.1: NaN3 / acetone / 0.17 h / 0 °C
6.1: toluene / 1 h / Heating
7.1: 108.8 mg / toluene / 27 h / Heating
8.1: NH2NH2 / methanol / 10 h / Heating
References:
Matsuo, Jun-ichi;Okano, Masahiko;Takeuchi, Kosuke;Tanaka, Hiroyuki;Ishibashi, Hiroyuki [Tetrahedron Asymmetry,2007,vol. 18,# 16,p. 1906 - 1910]
189101-41-5
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1067631-21-3
15 suppliers
$393.00/500mg
1655-07-8
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$6.00/5g
1067631-21-3
15 suppliers
$393.00/500mg