 
            Cocarboxylase synthesis
- Product Name:Cocarboxylase
- CAS Number:154-87-0
- Molecular formula:C12H19ClN4O7P2S
- Molecular Weight:460.7674
![2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazoniol-5-yl]ethyl dihydrogen diphosphate](/CAS/GIF/136-09-4.gif) 
                        
                        136-09-4
                        
                        
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                        154-87-0
                        
                        
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Yield:154-87-0 1.6 g
Reaction Conditions:
with hydrogenchloride in water at 40; pH=2 - 3;Reagent/catalyst;
Steps:
                    1-3; 1-3 Preparation of Thiamine Pyrophosphate
Steam the eluate at 40°C to 2-3ml, add concentrated hydrochloric acid to adjust the pH=2-3, use 2-3 times the amount of isopropanol to precipitate the product (1.6g), melting point: 238-241°C; purity: 96.55% .
                
References:
CN113402555,2021,A Location in patent:Paragraph 0043; 0049-0052; 0056-0058; 0062-0075
 
                        
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![Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,8,8-trihydroxy-4,6,8-trioxido-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)- (9CI)](/CAS/20211123/GIF/50851-39-3.gif) 
                        
                        50851-39-3
                        
                        
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                        67-03-8
                        
                        
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                        154-87-0
                        
                        
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                        $21.00/500mg
                        
                    
![3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-[2-(phosphonooxy)ethyl]thiazolium](/CAS/GIF/10023-48-0.gif) 
                        
                        10023-48-0
                        
                        
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                        4066-53-9
                        
                        
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                        154-87-0
                        
                        
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                        $21.00/500mg
                        
                    

 
          


