ChemicalBook CAS DataBase List Cuminaldehyde

Cuminaldehyde synthesis

11synthesis methods

Product Name:Cuminaldehyde
CAS Number:122-03-2
Molecular formula:C10H12O
Molecular Weight:148.2

From p-isopropylbenzyl chloride and hexamethylenetetramine (Arctander, 1969).

98-82-8
255 suppliers
$9.00/5ml

124-38-9
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$175.00/23402

122-03-2
324 suppliers
$6.00/25g

Yield:122-03-2 70.2%

Reaction Conditions:

Stage #1:carbon dioxide with zinc(II) cyanide;ruthenium trichloride;rhodium (III) acetate;cobalt(II) acetate;zirconium(IV) acetate for 1 h;Autoclave;
Stage #2:Isopropylbenzene at 50; under 15001.5 Torr; for 5 h;

Steps:

23 Example 23
In a 250mL autoclave, 381g of Me3NCl-AlCl, Rh (CH3COO) 3 containing 5g Rh, Co (CH3COO) containing 5g Co, Zr (CH3COO) 4 containing 5g Zr, RuCl3 containing 2g Ru and Zn (CN) 2, the air in the kettle was first replaced with N2 3 times, and then replaced with CO gas 3 times; stirred at 500 rpm for 1 hour; 50g of cumene was added, and then replaced with CO gas 3 times; the temperature was raised to 50 ° C and the CO pressure was maintained Stir at 2.0 MPa and 500 rpm and react for 5 h to obtain a product mixture containing p-methylbenzaldehyde.For comparison and explanation, the catalyst formulation, the conversion of cumene and the selectivity to p-cumylbenzaldehyde are listed in Table 1.

References:

Sinopec Corporation;Sinopec Corporation Shanghai Petrochemical Institute;Wang Yanhong;Xiao Zhongbin;Yang Yunxin CN110540490, 2019, A Location in patent:Paragraph 0110-0112; 0121

2055-40-5 Synthesis