DBCO-PEG4-SE synthesis
- Product Name:DBCO-PEG4-SE
- CAS Number:1427004-19-0
- Molecular formula:C34H39N3O10
- Molecular Weight:649.69
2222-33-5
325 suppliers
$6.00/5g
1427004-19-0
91 suppliers
$37.00/1MG
Yield:-
Steps:
Multi-step reaction with 8 steps
1: hydroxyamino hydrochloride; pyridine / ethanol / 15 h / Reflux
2: diisobutylaluminium hydride / dichloromethane; toluene / -5 - 20 °C
3: N-ethyl-N,N-diisopropylamine / dichloromethane / 4 h / 20 °C
4: bromine / dichloromethane / 2 h / 0 °C / Inert atmosphere
5: potassium-t-butoxide / tetrahydrofuran / 0.5 h / -40 °C / Inert atmosphere
6: N-[3-(N,N-dimethylamino)-propyl]-N'-ethyl-carbodiimide hydrochloride / dichloromethane / 20 °C
7: triethylamine / N,N-dimethyl-formamide / 20 °C
8: N-[3-(N,N-dimethylamino)-propyl]-N'-ethyl-carbodiimide hydrochloride / dichloromethane / 20 °C
References:
WO2018/89373,2018,A2
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34 suppliers
$28.60/1g
1427004-19-0
91 suppliers
$37.00/1MG
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23194-93-6
74 suppliers
$125.00/100mg
1427004-19-0
91 suppliers
$37.00/1MG
1353016-70-2
187 suppliers
$44.79/5MG
1427004-19-0
91 suppliers
$37.00/1MG
1353016-71-3
156 suppliers
$50.00/1mg
1427004-19-0
91 suppliers
$37.00/1MG