ChemicalBook CAS DataBase List DBCO-NHS Ester

DBCO-NHS Ester synthesis

9synthesis methods

Product Name:DBCO-NHS Ester
CAS Number:1353016-71-3
Molecular formula:C23H18N2O5
Molecular Weight:402.4

516-12-1 Synthesis

516-12-1
527 suppliers
$5.00/5g

1353016-70-2
148 suppliers
$44.79/5MG

1353016-71-3
112 suppliers
$50.00/1mg

Yield:-

Reaction Conditions:

with 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in N,N-dimethyl acetamide

Steps:

Fig. 13 shows the synthesis of an antibody conjugate via the phosphamide linkers containing two function groups, wherein one group is linked to a cytotoxic agent, MMAF for targeted killing, and the other one is linked to a fluorochrome group for monitoring the interaction of the conjugate with a targeted cell.

References:

SUZHOU M-CONJ BIOTECH CO., LTD;Zhao, Robert Yongxin US2015/284416, 2015, A1 Location in patent:Paragraph 0050

FullText

6066-82-6 Synthesis