Didodecyldimethylammonium bromide synthesis
- Product Name:Didodecyldimethylammonium bromide
- CAS Number:3282-73-3
- Molecular formula:C26H56BrN
- Molecular Weight:462.63
143-15-7
419 suppliers
$5.00/25g
124-40-3
501 suppliers
$18.00/100ml
112-18-5
359 suppliers
$5.00/25g
3282-73-3
182 suppliers
$36.39/2g
Yield:112-18-5 40% ，3282-73-3 46%
Reaction Conditions:
in water;benzene at 20 - 25; for 20 h;Reagent/catalyst;
Steps:
NH-Alkylation of dimethylamine with dodecyl bromide according to the described method. 5
A mixture of a 38% aqueous solution of dimethylamine (12.5 mL, 93.8 mmol) and dodecyl bromide (11.7 g, 46.9 mmol) in benzene (15 mL) was stirred at 20-25 °C for 20 h. Then, a 50% aqueous solution of NaOH (1.9 g, 46.9 mmol) was added to the reaction mixture, and the resulting mixture was evaporated in vacuo. The residue was dissolved in CHCl3 (20 mL), the formed precipitate was filtered off, and the filtrate was evaporated in vacuo. According to the 1H NMR spectral data, the isolated mixture contained amine 6a (4.1 g, 40%), N,N-didodecyl-N,N-dimethylammonium bromide (4.9 g, 46%), and unreacted dodecyl bromide (1.7 g, 14%).
References:
Kharlamov;Artyushin;Bondarenko [Russian Chemical Bulletin,2014,vol. 63,# 11,p. 2445 - 2454][Izv. Akad. Nauk, Ser. Khim.,2014,# 11,p. 2445 - 2454]
143-15-7
419 suppliers
$5.00/25g
124-40-3
501 suppliers
$18.00/100ml
3282-73-3
182 suppliers
$36.39/2g
4536-30-5
52 suppliers
$222.00/1ml
3282-73-3
182 suppliers
$36.39/2g
