Ethanone,1-(2-amino-5-bromo-4-chlorophenyl)- synthesis
- Product Name:Ethanone,1-(2-amino-5-bromo-4-chlorophenyl)-
- CAS Number:937816-91-6
- Molecular formula:C8H7BrClNO
- Molecular Weight:248.5
21402-26-6
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Yield:-
Reaction Conditions:
Stage #1: 4-bromo-3-chloroaniline;acetonitrilewith boron trichloride in n-heptane;
Stage #2: with aluminium trichloride in n-heptane;Heating;
Stage #3: with hydrogenchloride in n-heptane;Heating;Further stages.;
References:
Nittoli, Thomas;Curran, Kevin;Insaf, Shabana;DiGrandi, Martin;Orlowski, Mark;Chopra, Rajiv;Agarwal, Atul;Howe, Anita Y. M.;Prashad, Amar;Floyd, M. Brawner;Johnson, Bernard;Sutherland, Alan;Wheless, Karen;Feld, Boris;O'Connell, John;Mansour, Tarek S.;Bloom, Jonathan [Journal of Medicinal Chemistry,2007,vol. 50,# 9,p. 2108 - 2116]
89-77-0
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