ETHYL 2-[(4-HYDROXYPHENYL)SULFANYL]ACETATE synthesis
1synthesis methods
- Product Name:ETHYL 2-[(4-HYDROXYPHENYL)SULFANYL]ACETATE
- CAS Number:30519-00-7
- Molecular formula:C10H12O3S
- Molecular Weight:212.27
Yield:30519-00-7 95%
Reaction Conditions:
with triethylamine in chloroform at 25; for 2 h;
Steps:
19
A mixture of Et3N (2.5 g, 25 mmol) and 19-2 (3.3 g, 20 mmol) was added drop-wise to a solution of 19-1 (2.52 g, 20 mmol) in CHCl3 (50 mL) at 25 °C. The reaction mixture was stirred at 25 °C for 2 hours and was washed with water (2x50 mL), organic layer was separated, dried over Na2SO4, filtered and evaporated/dried in vacuo (4.0 g, 95%). The product was used without additional purification.
References:
WO2021/76886,2021,A1 Location in patent:Paragraph 0362