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ChemicalBook CAS DataBase List ETHYL 4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BENZOATE
850375-01-8

ETHYL 4-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BENZOATE synthesis

1synthesis methods
1H-Indole-3-acetic acid, α-oxo-, 2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)benzoyl]hydrazide

1312761-45-7
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: hydrazine hydrate / ethanol / 30 h / Reflux
2: triethylamine / tert-butyl methyl ether / 26.25 h / 0 - 20 °C

References:

Schmidt, Stefanie;Preu, Lutz;Lemcke, Thomas;Totzke, Frank;Sch?chtele, Christoph;Kubbutat, Michael H.G.;Kunick, Conrad [European Journal of Medicinal Chemistry,2011,vol. 46,# 7,p. 2759 - 2769]

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