ETHYL 5-AMINO-1-PHENETHYLPYRAZOLE-4-CARBOXYLATE synthesis
- Product Name:ETHYL 5-AMINO-1-PHENETHYLPYRAZOLE-4-CARBOXYLATE
- CAS Number:252903-25-6
- Molecular formula:C14H17N3O2
- Molecular Weight:259.3
156-51-4
96 suppliers
$48.00/100mg
94-05-3
285 suppliers
$5.00/5g
252903-25-6
13 suppliers
$180.00/100mg
Yield:252903-25-6 67%
Reaction Conditions:
Stage #1: 2-phenethylhydrazine sulfatewith sodium ethanolate in ethanol at 20; for 1 h;Inert atmosphere;
Stage #2: ethyl (ethoxymethylene)cyanoacetate in ethanol at 0 - 70; for 14.5 h;Inert atmosphere;regioselective reaction;
References:
Fandrick, Daniel R.;Sanyal, Sanjit;Kaloko, Joseph;Mulder, Jason A.;Wang, Yuwen;Wu, Ling;Lee, Heewon;Roschangar, Frank;Hoffmann, Matthias;Senanayake, Chris H. [Organic Letters,2015,vol. 17,# 12,p. 2964 - 2967] Location in patent:supporting information
51-71-8
79 suppliers
$35.00/25mg
94-05-3
285 suppliers
$5.00/5g
252903-25-6
13 suppliers
$180.00/100mg
103-63-9
513 suppliers
$9.00/10g
6994-25-8
412 suppliers
$5.00/1g
252903-25-6
13 suppliers
$180.00/100mg