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ethyl 5-(trifluoromethyl)isoxazole-3-carboxylate synthesis

4synthesis methods
1514-82-5 Synthesis
2-BROMO-3,3,3-TRIFLUOROPROPENE

1514-82-5
242 suppliers
$45.00/5G

14337-43-0 Synthesis
2-CHLORO-2-HYDROXYIMINOACETIC ACID ETHYL ESTER

14337-43-0
208 suppliers
$9.00/1g

ethyl 5-(trifluoromethyl)isoxazole-3-carboxylate

625120-13-0
20 suppliers
inquiry

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Yield:625120-13-0 69%

Reaction Conditions:

with sodium hydrogencarbonate in ethyl acetate at 20;regioselective reaction;

References:

Chalyk, Bohdan A.;Hrebeniuk, Kateryna V.;Fil, Yulia V.;Gavrilenko, Konstantin S.;Rozhenko, Alexander B.;Vashchenko, Bohdan V.;Borysov, Oleksandr V.;Biitseva, Angelina V.;Lebed, Pavlo S.;Bakanovych, Iulia;Moroz, Yurii S.;Grygorenko, Oleksandr O. [Journal of Organic Chemistry,2019,vol. 84,# 24,p. 15877 - 15899]

95080-93-6 Synthesis
(Z)-Ethyl 2-chloro-2-(hydroxyiMino)acetate

95080-93-6
1 suppliers
inquiry

1514-82-5 Synthesis
2-BROMO-3,3,3-TRIFLUOROPROPENE

1514-82-5
242 suppliers
$45.00/5G

ethyl 5-(trifluoromethyl)isoxazole-3-carboxylate

625120-13-0
20 suppliers
inquiry