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122535-03-9

ethyl furo[3,2-b]pyridine-6-carboxylate synthesis

4synthesis methods
27828-71-3 Synthesis
5-Hydroxynicotinic acid

27828-71-3
311 suppliers
$6.00/5g

ethyl furo[3,2-b]pyridine-6-carboxylate

122535-03-9
22 suppliers
inquiry

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Yield:-

Steps:

Multi-step reaction with 5 steps
1: thionyl chloride / Reflux
2: iodine; sodium carbonate / water / 2 h / 20 °C
3: triethylamine / dichloromethane / 0.5 h / 0 °C
4: triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide / tetrahydrofuran / 1 h / 20 °C
5: potassium fluoride / methanol / 1 h / 10 - 20 °C

References:

CN105418620,2016,A