Fmoc-Glu-OMe synthesis
- Product Name:Fmoc-Glu-OMe
- CAS Number:145038-49-9
- Molecular formula:C21H21NO6
- Molecular Weight:383.39
![L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) 1-methyl ester](/CAS/20210111/GIF/160002-61-9.gif)
160002-61-9
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145038-49-9
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Yield: 96%
Reaction Conditions:
with trifluoroacetic acid in dichloromethane at 20; for 1 h;Inert atmosphere;Schlenk technique;
Steps:
3.2 tert-Butyl deprotection
General procedure: 1 eq of the respective starting material was dissolved in 10 ml of a 1:1 mixture of DCM and TFAper mmol. The solution was stirred at room temperature for 1 h until the development of bubbleshad ceased. The solvent was removed under reduced pressure and the oily residue was taken upin as little DCM as possible and precipitated from hexane, yielding a white precipitate which wasidentified as the product
References:
Daubit, Isabelle Marie;Wolf, Jonas;Metzler-Nolte, Nils [Journal of Organometallic Chemistry,2020,vol. 909,art. no. 121096] Location in patent:supporting information
6384-08-3
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82911-69-1
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145038-49-9
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71989-18-9
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145038-49-9
66 suppliers
$9.00/250mg