Fmoc-Ser(O-propargyl)-OH synthesis
- Product Name:Fmoc-Ser(O-propargyl)-OH
- CAS Number:1354752-75-2
- Molecular formula:C21H19NO5
- Molecular Weight:365.38
82911-69-1
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145205-94-3
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1354752-75-2
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Yield:1354752-75-2 74%
Reaction Conditions:
Stage #1: (S)-2-[(tert-butoxycarbonyl)amino]-3-(prop-2-yn-1-yloxy)propanoic acidwith trifluoroacetic acid at 0; for 1 h;Inert atmosphere;
Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimidewith potassium carbonate in 1,4-dioxane;water at 0 - 20; for 3.5 h;Inert atmosphere;
References:
Sminia, Tjerk Jacco;Pedersen, Daniel Sejer [Synlett,2012,vol. 23,# 18,p. 2643 - 2646,4] Location in patent:supporting information Sminia, Tjerk Jacco;Pedersen, Daniel Sejer [Synlett,2012,vol. 23,# 18,p. 2643 - 2646] Location in patent:supporting information
145205-94-3
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1354752-75-2
40 suppliers
$72.79/250MG
1379150-93-2
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82911-69-1
669 suppliers
$7.00/25g
1354752-75-2
40 suppliers
$72.79/250MG
![L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-2-propyn-1-yl-, methyl ester](/CAS/20210305/GIF/675585-14-5.gif)
675585-14-5
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1354752-75-2
40 suppliers
$72.79/250MG