IMidazo[1,2-a]pyridine-7-carbohydrazide, 95% synthesis
- Product Name:IMidazo[1,2-a]pyridine-7-carbohydrazide, 95%
- CAS Number:421595-78-0
- Molecular formula:C8H8N4O
- Molecular Weight:176.18
![Methyl imidazo[1,2-a]pyridine-7-carboxylate](/CAS/GIF/86718-01-6.gif)
86718-01-6
103 suppliers
$18.00/250mg
421595-78-0
18 suppliers
$73.00/250mg
Yield:421595-78-0 100%
Reaction Conditions:
with hydrazine hydrate in methanol;Reflux;
Steps:
A11.a
Hydrazine monohydrate (10 ml, 636 mmol) was added to methyl imidazo[1,2-a]pyridine-7-carboxylate (CAS: 86718-01-6) (11.2 g, 63.57 mmol) in solution in MeOH (300 ml). The reaction mixture was refluxed for 3 hours, then additional hydrazine monohydrate (10 ml, 636 mmol) was added and the mixture was refluxed overnight. After cooling to room temperature, the precipitate was filtered, washed with EtOH and dried yielding 13 g (quantitative) of intermediate shown.
References:
US2012/41000,2012,A1 Location in patent:Page/Page column 43
![ETHYL IMIDAZO[1,2-A]PYRIDINE-7-CARBOXYLATE 98](/CAS/GIF/372147-49-4.gif)
372147-49-4
58 suppliers
$31.00/1g
421595-78-0
18 suppliers
$73.00/250mg
13362-30-6
137 suppliers
$6.00/250mg
421595-78-0
18 suppliers
$73.00/250mg