ChemicalBook CAS DataBase List Imidazo[1,2-a]pyridine-7-carboxylic acid (9CI)

Imidazo[1,2-a]pyridine-7-carboxylic acid (9CI) synthesis

2synthesis methods

Product Name:Imidazo[1,2-a]pyridine-7-carboxylic acid (9CI)
CAS Number:648423-85-2
Molecular formula:C8H6N2O2
Molecular Weight:162.15

86718-01-6 Synthesis

Methyl imidazo[1,2-a]pyridine-7-carboxylate

86718-01-6
103 suppliers
$18.00/250mg

Imidazo[1,2-a]pyridine-7-carboxylic acid (9CI)

648423-85-2
102 suppliers
$48.00/250mg

Yield: 100%

Reaction Conditions:

with hydrogenchloride;water at 50; for 64 h;

Steps:

43
The title compound of Preparation 42 was dissolved in 100ml of HCI 37%. The reaction mixture was heated at 50⁰C for 64h. After this time the mixture was concentrated to dryness and dried in the vacuum oven to give 1.95g of the title compound as a solid (yield=100%).LRMS: m/z 163 (M+1 )⁺ Retention time: 0.41 min (method A)¹H NMR (200 MHz, DMSO-d₆) ppm 7.79 (d, J=8Hz, 1 H), 8.31 (s, 1 H), 8.38(s,1 H), 8.48(s,1 H), 8.97(d,J=8Hz, 1 H) Yield 99.9%

References:

ALMIRALL, S.A.;GRIMA POVEDA, Pedro Manuel;AGUILAR IZQUIERDO, Nuria;MIR CEPEDA, Marta;LOPEZ MARTINEZ, Manuel WO2010/43377, 2010, A1 Location in patent:Page/Page column 54

874-39-5 Synthesis

874-39-5
85 suppliers
$30.00/250mg

648423-85-2
102 suppliers
$48.00/250mg

References

Imidazo[1,2-a]pyridine-7-carboxylic acid (9CI) Related Search:

ETHYL IMIDAZO[1,2-A]PYRIDINE-7-CARBOXYLATE 98 IMidazo[1,2-a]pyridine-7-carbohydrazide, 95% 6-METHYLIMIDAZO[1,2-A]PYRIDINE METHYL IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLATE IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID 7-Methylimidazo(1,2-a)pyridine 3-BROMO-7-CHLOROIMIDAZO [1,2-A]PYRIDINE Methyl imidazo[1,2-a]pyridine-7-carboxylate Imidazo[1,2-a]pyridin-8-ol (9CI) 3-BROMO-7-METHYL-IMIDAZO[1,2-A]PYRIDINE