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ChemicalBook CAS DataBase List LHRH (1-5)

LHRH (1-5) synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: 78 percent / dioxane / 5 h / papain, dithioerythritol in phosphate buffer, pH 9
2: deprotection
3: 67 percent / methanol; H2O / 16 h / Ambient temperature; papain, dithioerythritol, pH 8
4: TFA, anisole / 3 h / 0 °C

References:

Slomczynska, Urszula;Leplawy, Tomasz;Leplawy, Miroslaw, T. [Zeitschrift fur Naturforschung, B: Chemical Sciences,1992,vol. 47,# 10,p. 1424 - 1430]

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