Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
logo
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook

Welcome back!

Structured search
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List Maytansine
35846-53-8

Maytansine synthesis

5synthesis methods
Spiro[2-azabicyclo[16.3.1]docosa-1(22),6,13,15,18,20-hexaene-11,2'-[1,3]dithian]-3-one, 9-[(aminocarbonyl)oxy]-21-chloro-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-12,20-dimethoxy-2,6,8,16-tetramethyl-, [5S-(5R*,6E,8R*,9R*,12S*,13E,15E)]- (9CI)

75349-68-7
0 suppliers
inquiry

Maytansine

35846-53-8
76 suppliers
inquiry

-

Yield:-

Steps:

Multi-step reaction with 6 steps
1: mercuric chloride, aq. calcium carbonate / acetonitrile / 12 h / 25 °C
2: 83 percent / aq. HF / acetonitrile / 0.75 h / 0 °C
3: 0.1 percent p-toluenesulfonic acid / 0.5 h / 25 °C
4: 87 percent / tert-butyl hydroperoxide, oxyvanadium(IV) bis(acetylacetonate), 2,6-lutidine / benzene; toluene / 3.5 h / 25 °C
5: imidazole / dimethylformamide; 1,2-dimethoxy-ethane / 75 h / 45 - 47 °C
6: 95 percent / aq. pyridinium chloride / tetrahydrofuran / 14 h / 25 °C

References:

Corey;Weigel;Chamberlin;et al. [Journal of the American Chemical Society,1980,vol. 102,# 21,p. 6613 - 6615]

Maytansine, 3-O-de[2-(acetylmethylamino)-1-oxopropyl]-4,5-deepoxy-4,5-didehydro-, (4E)- (9CI)

75340-67-9
0 suppliers
inquiry

Maytansine

35846-53-8
76 suppliers
inquiry

References
Maytansine, 3-O-de[2-(acetylmethylamino)-1-oxopropyl]-4,5-deepoxy-4,5-didehydro-9-O-methyl-, (4E)- (9CI)

75349-70-1
0 suppliers
inquiry

Maytansine

35846-53-8
76 suppliers
inquiry

References
Spiro[2-azabicyclo[16.3.1]docosa-1(22),6,13,15,18,20-hexaene-11,2'-[1,3]dithian]-3-one, 21-chloro-5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-9-hydroxy-12,20-dimethoxy-2,6,8,16-tetramethyl-, [5S-(5R*,6E,8R*,9R*,12S*,13E,15E)]- (9CI)

75340-66-8
0 suppliers
inquiry

Maytansine

35846-53-8
76 suppliers
inquiry

References
Maytansine, 3-O-de[2-(acetylmethylamino)-1-oxopropyl]-4,5-deepoxy-4,5-didehydro-3-O-[(1,1-dimethylethyl)dimethylsilyl]-, (4E)- (9CI)

75349-69-8
0 suppliers
inquiry

Maytansine

35846-53-8
76 suppliers
inquiry

References

Maytansine Related Search:

Exemestane Nintedanib Capecitabine 2-Chloro-3-methoxyaniline 3-[2-(dimethylamino)ethoxy]-N,N-dimethylpropylamine