
Methyl 4-cyclobutylbenzoate synthesis
- Product Name:Methyl 4-cyclobutylbenzoate
- CAS Number:1378655-16-3
- Molecular formula:C12H14O2
- Molecular Weight:190.2384

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Yield:1378655-16-3 92%
Reaction Conditions:
Stage #1: 4-methoxycarbonylphenyl bromidewith bis(tricyclohexylphosphine)nickel(II) dichloride;N-(phenyl(pyridin-2-yl)methyl)picolinamide;magnesium chloride;zinc in N,N-dimethyl acetamide;Inert atmosphere;
Stage #2: Bromocyclobutane in N,N-dimethyl acetamide at 80;Inert atmosphere;
References:
Han, Dongyang;Sun, Jie;Jin, Jian [Chemistry - An Asian Journal,2023,vol. 18,# 2,art. no. E202201132] Location in patent:supporting information

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619-42-1
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1378655-16-3
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