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ChemicalBook CAS DataBase List MFCD01134714
22453-82-3

MFCD01134714 synthesis

2synthesis methods
-

Yield:22453-82-3 59.1%

Reaction Conditions:

in ethanol; for 5 h;Reflux;

Steps:

General procedure for the preparation of 2-thioxo-3-(o-aryl)-quinazolin-4-ones (1a-f).

General procedure: Compounds 1a-f, 2-thioxo-3-(o-aryl)-quinazolin-4-ones, were synthesized by refluxing the appropriate isothiocyanates with anthranilic acid in ethanol for 5 h. The compounds were purified by recrystallization from ethanol.

References:

Hakgor, Ari;Erol Gunal, Sule [Tetrahedron,2021,vol. 100,art. no. 132506]