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ChemicalBook CAS DataBase List N-(4-FLUOROBENZYL)BUTAN-1-AMINE
60509-35-5

N-(4-FLUOROBENZYL)BUTAN-1-AMINE synthesis

3synthesis methods
-

Yield:60509-35-5 49%

Reaction Conditions:

Stage #1: para-fluorobenzylaminewith caesium carbonate in N,N-dimethyl-formamide at 25; for 0.5 h;
Stage #2: 1-bromo-butane in N,N-dimethyl-formamide at 25; for 24 h;Microwave irradiation;chemoselective reaction;

References:

Castillo, Juan-Carlos;Orrego-Hernández, Jessica;Portilla, Jaime [European Journal of Organic Chemistry,2016,vol. 2016,# 22,p. 3824 - 3835]