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ChemicalBook CAS DataBase List N-(4-Fluorobenzyl)cyclopentylaMine, 97%
85952-73-4

N-(4-Fluorobenzyl)cyclopentylaMine, 97% synthesis

1synthesis methods
-

Yield:85952-73-4 61%

Reaction Conditions:

Stage #1: 4-fluorobenzaldehyde;Cyclopentamine in dichloromethane at 25;Molecular sieve;
Stage #2: with sodium triacetoxy borohydride in dichloromethane at 25;

References:

Giroud, Maude;Harder, Michael;Kuhn, Bernd;Haap, Wolfgang;Trapp, Nils;Schweizer, W. Bernd;Schirmeister, Tanja;Diederich, Fran?ois [ChemMedChem,2016,vol. 11,# 10,p. 1042 - 1047] Location in patent:supporting information