N-Ethoxycarbonyl α-Methyl-L-valine synthesis
1synthesis methods
- Product Name:N-Ethoxycarbonyl α-Methyl-L-valine
- CAS Number:952577-51-4
- Molecular formula:C9H17NO4
- Molecular Weight:203.24
Yield:-
Reaction Conditions:
Stage #1:(S)-2-amino-2,3-dimethylbutyronitrile with sulfuric acid in water at 100;
Stage #2:chloroformic acid ethyl ester with sodium hydroxide in water; pH=9.8 - 10.2 for 2.5 h;Further stages.;Schotten-Baumann reaction;
References:
Kuethe, Jeffrey T.;Gauthier Jr., Donald R.;Beutner, Gregory L.;Yasuda, Nobuyoshi [Journal of Organic Chemistry,2007,vol. 72,# 19,p. 7469 - 7472]