N'-HYDROXY-2-THIOPHENECARBOXIMIDAMIDE synthesis
- Product Name:N'-HYDROXY-2-THIOPHENECARBOXIMIDAMIDE
- CAS Number:53370-51-7
- Molecular formula:C5H6N2OS
- Molecular Weight:142.18
1003-31-2
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$6.00/5g
53370-51-7
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$17.00/250mg
Yield: 100%
Reaction Conditions:
with hydroxylamine monohydrate in ethanol at 90; for 1.5 h;Sealed tube;
Steps:
4.1.4. General procedure for the synthesis of amidoximes (39e52)
General procedure: In a pressurized sealed vial, aqueous hydroxylamine 50% w/w (4equiv) was added to a stirred solution of the appropriate carbonitrile(1 equiv) in absolute ethanol. The resulting mixture washeated at 90 C for 1 h. The solvent was then evaporated to drynessproviding the desired amidoxime quantitatively, which was usedwithout further purification.
References:
Quadri, Marta;Silnović, Almin;Matera, Carlo;Horenstein, Nicole A.;Stokes, Clare;De Amici, Marco;Papke, Roger L.;Dallanoce, Clelia [European Journal of Medicinal Chemistry,2018,vol. 160,p. 207 - 228]
1003-31-2
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$6.00/5g
5470-11-1
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$10.00/5 g
584-08-7
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$5.00/100g
53370-51-7
79 suppliers
$17.00/250mg
617-90-3
143 suppliers
$11.00/1g
53370-51-7
79 suppliers
$17.00/250mg