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ChemicalBook CAS DataBase List N-HYDROXY-BUTYRAMIDINE

N-HYDROXY-BUTYRAMIDINE synthesis

8synthesis methods
-

Yield:4312-91-8 94%

Reaction Conditions:

Stage #1: butan-1-olwith 1-hydroxy-pyrrolidine-2,5-dione;[bis(acetoxy)iodo]benzene in acetonitrile at 0 - 20; for 3 h;Inert atmosphere;Green chemistry;
Stage #2: with hydroxylamine in water;acetonitrile; for 12 h;Inert atmosphere;Green chemistry;

References:

Dettori, Giovanna;Gaspa, Silvia;Porcheddu, Andrea;De Luca, Lidia [Organic and Biomolecular Chemistry,2014,vol. 12,# 26,p. 4582 - 4585] Location in patent:supporting information