ChemicalBook CAS DataBase List N-Methyl-1-amino-hex-5-ene

N-Methyl-1-amino-hex-5-ene synthesis

5synthesis methods

Product Name:N-Methyl-1-amino-hex-5-ene
CAS Number:55863-02-0
Molecular formula:C7H15N
Molecular Weight:113.2

2695-47-8

74-89-5

55863-02-0

The following step: To a reaction flask was added a methanol solution containing 25% methylamine in an amount of 10 equivalents of methylamine. Subsequently 1 equivalent of 6-bromo-1-hexene was added to the reaction flask and mixed with stirring. The reaction mixture was heated to 40°C in an oil bath and kept at this temperature for 3 hours. Upon completion of the reaction, the mixture was cooled to 20 °C and 0.1 equivalent of p-methoxyphenol was added as a stabilizer, along with 1 equivalent of sodium hydroxide. The excess methylamine methanol solution was recovered under negative pressure. Next, the mixture was heated to 50 °C and a colorless liquid product, N-methyl-5-hexen-1-amine, was obtained by distillation under reduced pressure. The yield of this step was 67% and the purity of the product was 96.5%.

2695-47-8 Synthesis

2695-47-8
296 suppliers
$14.00/5g

74-89-5 Synthesis

74-89-5
0 suppliers
$13.44/25ML

55863-02-0
78 suppliers
$32.00/250mg

Yield:55863-02-0 67%

Reaction Conditions:

in methanol at 40; for 3 h;Solvent;Temperature;

Steps:

9 Example 9: A synthesis process of N-methyl-5-hexen-1-amine, which differs from Example 1 in that it includes

The following steps: adding 25% methylamine in methanol to the reaction flask, the methylamine content is 10 equivalents,Add 1 equivalent of 6-bromo-1-hexene to the reaction flask, stir, and heat the oil bath to 40° C. After 3 hours of reaction, cool down to 20° C. and add 0.1 equivalent of stable.Stabilizer, stabilizing agent is p-methoxy phenol, 1 equivalent of sodium hydroxide is added, excess methylamine methanol solution is recovered under negative pressure, heated to 50°C,Distillation under reduced pressure gave a colorless liquid, which was N-methyl-5-hexen-1-amine, with a yield of 67% and a purity of 96.5%.

References:

CN108003037,2018,A Location in patent:Paragraph 0014-0028